Karela (Momordica charantia), commonly known as Bitter Melon, is a medicinal plant renowned for its anti-diabetic, antioxidant, and anti-inflammatory properties. Its extracts, rich in bioactive compounds like charantin, polypeptide-P, and momordicin, are widely used in herbal medicine, pharmaceuticals, and nutraceuticals to support blood sugar regulation, liver health, and immune function. Extraction processes typically involve solvent extraction or aqueous methods to preserve these active constituents for use in supplements and therapeutic formulations.